A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #

Thiopuirne Methyltransferase Activity, Erythrocytes

Test Code
TPMT


Alias/See Also
TPMT Activity


Preferred Specimen
5 mL sodium heparin whole blood


Minimum Volume
3 mL


Other Acceptable Specimens
EDTA whole blood


Transport Container
Original collection vial


Transport Temperature
Refrigerated


Specimen Stability
6 days refrigerated


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis


Report Available
4-7 days


Reference Range
See report for normal ranges


Clinical Significance
Thiopurine methyltransferase (TPMT) deficiency is a condition in which patients treated with standard doses of the immunosuppressant azathioprine (AZA, Imuran) or the antineoplastic drug 6-mercaptopurine (6-MP, Purinethol) may develop life-threatening myelosuppression or severe hematopoietic toxicity.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.