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Soluble Transferrin receptor

Test Code
SOLTR


Alias/See Also
sTfR


Preferred Specimen
1 mL serum


Minimum Volume
0.3 mL


Transport Container
Plastic vial


Transport Temperature
Ambient temperature


Specimen Stability
72 hours ambient, 7 days refrigerated


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis


Report Available
2-4 days


Reference Range
1.8-4.6 mg/L


Clinical Significance
The concentration of sTfR is an indicator of iron status. Iron deficiency causes overexpression of transferrin receptor and sTfR levels, while iron repletion results in decreased sTfR levels. While ferritin measurement is the accepted method for assessment of iron deficiency, ferritin is an acute-phase reactant and elevates in response to processes that do not correlate with iron status, including inflammation, chronic disease, malignancy, and infection. sTfR is not an acute-phase reactant and the interpretation of iron status using sTfR measurement is not affected by these confounding pathologies.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.