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Immunoglobulin Free Light Chains, Serum
Test CodeIFLC
Alias/See Also
Serum Free Light chains, Kappa Free Ligth Chain, Lambda Free Light Chain
Preferred Specimen
1 mL serum
Minimum Volume
0.5 mL
Transport Container
Plastic vial
Transport Temperature
Ambient temperature
Specimen Stability
3 days ambient
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross Lipemia
Report Available
2-3 days
Reference Range
See report for normal ranges.
Clinical Significance
The monoclonal gammopathies are characterized by a clonal expansion of plasma cells that secrete a monoclonal immunoglobulin (Ig). The monoclonal Ig secreted by these cells serves as a marker of the clonal proliferation, and the quantitation of monoclonal protein can be used to monitor the disease course.