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Felbamate level
Test CodeFELBA
Preferred Specimen
1 mL serum
Minimum Volume
0.5 mL
Transport Container
Plastic vial
Transport Temperature
Refrigerated
Specimen Stability
Refrigerated 14 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis, gross lipemia, gross icterus
Report Available
2-4 days
Reference Range
30.0-60.0 mcg/mL
Clinical Significance
Felbamate is an anticonvulsant drug approved for treatment of partial seizures with or without secondary generalization in persons >14 years of age. It is also approved for Lennox-Gastout syndrome in children >2 years of age. Felbamate is well absorbed (>90%) and is metabolized by the hepatic cytochrome P450 system. Metabolites lack anticonvulsant activity.