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Cutaneous Immunofluorescence Antibodies IgG
Test CodeCIAS
Preferred Specimen
2 mL serum
Minimum Volume
0.5 mL
Transport Container
Plastic vial
Transport Temperature
Refrigerated
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis, gross lipemia, gross icterus
Report Available
7-10 days
Reference Range
Negative in normal individuals
Clinical Significance
IgG anti-basement zone (BMZ) antibodies are produced by patients with pemphigoid. In most patients with bullous pemphigoid, serum contains IgG anti-BMZ antibodies, while in cicatricial pemphigoid circulating IgG anti-BMZ antibodies are found in a minority of cases.