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BCR/ABL translocation 9;22, FISH

Test Code
BCRABL


Alias/See Also
BCR/ABL FISH


Preferred Specimen
7-10 mL sodium heparin whole blood


Minimum Volume
2 mL


Other Acceptable Specimens
1-2 mL Bone Marrow


Transport Container
Sodium Heparin tube


Transport Temperature
Ambient temperature


Specimen Stability
Deliver ASAP


Report Available
8-12 days


Reference Range
An interpretive report will be provided.


Clinical Significance
Chronic myelogenous leukemia (CML) is a hematopoietic stem cell neoplasm included in the broader diagnostic category of myeloproliferative neoplasms. CML is consistently associated with fusion of the breakpoint cluster region gene (BCR) at chromosome 22q11 to the Abelson gene (ABL) at chromosome 9q23. This fusion is designated BCR/ABL and may be seen on routine karyotype as the Philadelphia chromosome




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.