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Cytoplasmic Neutrophil Ab
Test CodeANC
Alias/See Also
ANCA, Panca, Canca
Preferred Specimen
1 mL serum
Minimum Volume
0.4 mL
Transport Container
Plastic vial
Transport Temperature
Refrigerated temperature
Specimen Stability
14 days refrigerated
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross lipemia, Gross hemolysis
Report Available
2-5 days
Reference Range
Negative
Clinical Significance
Antineutrophil cytoplasmic antibodies (ANCA) can occur in patients with autoimmune vasculitis including Wegener's granulomatosis (WG), microscopic polyangiitis (MPA), or organ-limited variants thereof such as pauci-immune necrotizing glomerulonephritis. Detection of ANCA is a well-established diagnostic test for the evaluation of patients suspected of having autoimmune vasculitis