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Creatinine Clearance
Test CodeCRCL
Includes
Creatinine (serum and urine), Creatinine Clearance (calculation)
Preferred Specimen
Minimum Volume
Urine: 1 mL
Serum: 0.5 mL
Serum: 0.5 mL
Other Acceptable Specimens
Heparinized plasma is acceptable for blood level.
Instructions
Record total volume and collection duration on specimen container and test requisition. Indicate the patient's height (in feet and inches) and weight (in lbs.) on test requisition.
Note: A serum creatinine level must be collected within 24 hours of the beginning or ending of the urine collection.
Note: A serum creatinine level must be collected within 24 hours of the beginning or ending of the urine collection.
Transport Container
Urine: Plastic screw-cap container
Serum: Transport tube
Serum: Transport tube
Transport Temperature
Ambient
Specimen Stability
Ambient: 2 days
Refrigerated: 6 days
Refrigerated: 6 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Grossly icteric serum
Methodology
Spectrophotometry (SP)
Setup Schedule
24/7
Report Available
Same day
Reference Range
See report
Clinical Significance
Creatinine Clearance is used to evaluate the glomerular filtration rate (GFR). Clearance is defined as that volume of plasma from which a measured amount of substance could be completely eliminated into the urine per unit of time. Daily creatinine production is fairly constant except when there is massive injury to muscle.
