Chloride

Test Code
CL


Preferred Specimen
1 mL serum


Minimum Volume
0.5 mL


Other Acceptable Specimens


Heparinized plasma




Transport Container
Serum separator tube (SST)


Transport Temperature
Ambient


Specimen Stability
 Ambient: 7 days
Refrigerated: 7 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Anticoagulants other than heparin


Methodology
Ion Selective Electrode (ISE)

Setup Schedule
24/7


Report Available
Same day


Limitations
Patients recently exposed to bromide may have elevated results.


Reference Range
99-110 mmol/L


Clinical Significance
Serum chloride is the major extracellular anion and counter-balances the major cation, sodium, maintaining electrical neutrality of the body fluids. Two thirds of the total anion concentration in extracellular fluids is chloride and it is significantly involved in maintaining proper hydration and osmotic pressure. Movement of chloride ions across the red blood cell membrane is essential for the transport of biocarbonate ions in response to changing concentrations of carbon dioxide. Chloride measurements are used in the diagnosis and treatment of electrolyte and metabolic disorders such as cystic fibrosis and diabetic acidosis.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.