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Troponin I, High Sensitivity
Test CodeTROP
Preferred Specimen
1 mL Serum
Minimum Volume
0.2 mL
Other Acceptable Specimens
Heparinized plasma
Instructions
Minimize exposure to room temperature.
Transport Container
Original collection vial
Transport Temperature
Ambient
Specimen Stability
Ambient: 8 hours
Refrigerated: 24 hours
Frozen: 7 days
Refrigerated: 24 hours
Frozen: 7 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature • Received refrigerated • EDTA plasma • Sodium heparin (green-top) tube
Methodology
Immunoassay (IA)
Setup Schedule
24/7
Report Available
Same day
Limitations
Non-acute coronary syndromes may cause troponin elevation.
Reference Range
≤0.05 ng/mL
Clinical Significance
Troponin I is part of a protein complex which regulates the contraction of striated muscle. In acute coronary syndromes (ACS), it can be detected in blood at 4-8 hours following the onset of chest pain, reaches a peak concentration at 12-16 hours, and remains elevated for 5-9 days. Troponin I has been used as a reliable marker in the diagnosis of perioperative myocardial infarction in patients undergoing cardiac surgery.
