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Tobramycin, Peak
Test CodeTOBP
Preferred Specimen
1 mL serum collected in a red-top tube (no gel)
Patient Preparation
Collect 30 minutes after end of IV infusion or 60-90 minutes after IM dose
Minimum Volume
0.2 mL
Other Acceptable Specimens
Heparinized plasma (NO GEL)
Transport Container
Transport tube
Transport Temperature
Refrigerated (cool packs)
Specimen Stability
Refrigerated: 3 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum separator tube or Plasma Separator tube
Methodology
Immunoassay (IA)
Setup Schedule
24/7
Report Available
Same day
Reference Range
6.0-10.0 ug/mL
Clinical Significance
Tobramycin is an aminoglycoside antibiotic used in the treatment of gram-negative bacterial infections, especially Pseudomonas, Proteus, Klebsiella and also Staphylococcus. Tobramycin is potentially nephrotoxic and ototoxic and serial monitoring of peak and trough serum levels may provide the clinician with information to maintain safe and therapeutic levels.
