Maternal Serum AFP Only

Test Code

AFPNTD

Includes

AFP, Maternal Risk Interpretation

Preferred Specimen

1 mL serum

Minimum Volume

0.5 mL

Instructions

Complete University of Iowa Hygienic Lab Maternal Test Form

Transport Container

Original collection vial

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 7 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Grossly lipemic

Methodology
Immunoassay (IA)

FDA Status
This test code is for non-New York patient testing. For New York patient testing, use test code 92788.

Setup Schedule

Monday-Friday

Report Available

4-9 days

Limitations

MSAFP results consistent with increased risk of NTD may be followed-up with appropriate diagnostic testing as detailed in the report. MSAFP does not screen for chromosomal abnormalities.

Clinical Significance

Maternal serum alpha-fetoprotein (MSAFP) is used for prenatal screening. Maternal serum Alpha-Fetoprotein (AFP) elevation is associated with open neural tube defects, multiple gestation, placental anomalies, ventral abdominal wall defects, congenital nephrosis, and oligohydramnios. Follow-up for abnormal AFP results include genetic counseling, level II or III ultrasound examination and consideration of amniocentesis for chromosome and AFP analysis. MSAFP is not to be used as a screening test for chromosomal abnormalities.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.