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Sickle Cell Screen
Test CodeSCELL
Preferred Specimen
3 mL EDTA whole blood
Minimum Volume
0.5 mL EDTA whole blood
Other Acceptable Specimens
None
Instructions
None
Transport Container
Original collection tube
Transport Temperature
Room temperature
Specimen Stability
Refrigerated: 7 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • Clotted
Methodology
Solubility
Setup Schedule
24/7
Report Available
Same day
Limitations
Testing should not be performed in children under 6 months of age. Positive screen results should be confirmed with hemoglobin electrophoresis.
Reference Range
Negative
Clinical Significance
This is a screening test to determine the presence of sickling hemoglobins. (e.g. hemoglobin-s, hemoglobin c-Harlem). It is important to detect Hb-S in order to determine which individuals are at risk of crisis when exposed to prolonged anoxia such as may occur during surgery, athletic programs or high altitude conditions.