Codeine and Metabolite - Free (Unconjugated), Serum/Plasma

Test Code

CODE

Includes

Codeine, Free and Morphine, Free (Metabolite)

Preferred Specimen

1 mL serum collected in a red-top tube (no gel)

Minimum Volume

0.4 mL

Other Acceptable Specimens

Plasma collected in: EDTA (lavender-top) tube or EDTA (pink-top) tube

Instructions

Promptly centrifuge and separate serum or plasma into a transport tube

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 30 days
Refrigerated: 30 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Serum separator tube (SST) • PST

Methodology
Gas Chromatography/Mass Spectrometry (GC/MS)

FDA Status
This test was developed and its performance characteristics determined by NMS Labs. It has not been cleared or approved by the US Food and Drug Administration.

Setup Schedule

Mon-fri

Report Available

4-6 days

Reference Range

See Laboratory Report

Clinical Significance

Codeine and morphine are narcotic analgesics. Codeine is also used as an antitussive. Both exhibit half-lives of 2-3 hours. Side effects of therapeutic use of these drugs, and effects of excessive use are similar, differing only in degree. Among these effects, the more serious ones are confusion and anxiety, respiratory depression and the development of physical dependence.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.