Fibrinogen

Test Code
FIBR


Preferred Specimen
Sodium citrate tube filled to correct volume


Patient Preparation
Overnight fasting is required

Minimum Volume
0.5 mL frozen plasma


Other Acceptable Specimens
1 mL frozen platelet poor sodium citrate plasma


Instructions

Avoid hemolysis. Avoid lipemia.



Transport Container
Transport tube


Transport Temperature
Ambient


Specimen Stability
 AmbientAmbient: 4 hours 
Refrigerated: 4 hours
Frozen: 14 days


Methodology
Nephelometry

Setup Schedule
24/7


Report Available
Same day


Reference Range
Fibrinogen Antigen, Neph <350 mg/dL
Risk  
  Optimal < 350 mg/dL
  High ≥ 350 mg/dL
Adult cardiovascular event risk category cut points (optimal, high) are based on Siemens BN II and BN ProSpec®  system package insert.


Clinical Significance
Low levels of fibrinogen are associated with bleeding most commonly secondary to liver disease or Disseminated Intravascular Coagulation (DIC). Fibrinogen is an acute phase reactant and thus elevated levels may be associated with inflammation. Increased concentrations are also associated with increased risk of atherosclerosis.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.