Testosterone,Total

Test Code
TEST


Alias/See Also
Total Testosterone


CPT Codes
84403

Preferred Specimen

Green




Minimum Volume
0.5 mL


Other Acceptable Specimens
Lithium Heparin Plasma (green top) tube


Transport Container

Serum (gold top) tube or Lithium Heparin Plasma (green top) tube



Transport Temperature
Room Temperature or Refrigeration


Specimen Stability
Room Temperature - 1 day; Refrigerated - 7 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis, Turbidity, Quantity Not Sufficient, IV contamination


Methodology
Chemiluminescence

Setup Schedule

Daily upon receipt



Report Available
Upon completion of analysis


Limitations
Inaccurate results may be caused by steroid therapy or physiological conditions causing large changes in serum protein concentrations. Testosterone concentrations may be elevated due to defects in steroid metabolism remote from the hypothalamic-pituitary-gonadal axis.


Reference Range

Females with normal menstral cycles: 6-77 ng/dL
Males:  132 - 813 ng/dL



Clinical Significance

Testosterone is produced by the adrenals, the theca cells in the ovary and the leydig cells in the testes. As much as 97% of circulating testosterone is bound to serum proteins such as sex hormone binding globulin (SHBG). In the male, testosterone stimulates the maturation of genitalia and secondary sexual characteristics and its measurement is used to investigate sexual dysfunction in juveniles and adults. In females testosterone concentrations are much lower and an elevated concentration may indicate polycystic ovarian syndrome among other conditions. Clinical symptoms of testosterone excess in females include infertility, amenorrhea, obesity and hirsutism.





The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.