Aptt-Lupus Anticoagulant

Test Code

PTTLA

CPT Codes
85303

Preferred Specimen

1 Blue

Minimum Volume

Blue top must be filled to Minimum Fill Indicator Line on tube.

Other Acceptable Specimens

none

Instructions

Test is part of the Lupus Anticoagulant profile. Outreach clients should double-spin the blue top plasma, remove the plasma from the RBC button, and freeze in a polypropylene tube.

Transport Container

BLUE, polypropylene tube

Transport Temperature

Blue - RT; polypropylene - frozen

Specimen Stability

Blue - 4 hours ambient; Plasma - 4 hours RT, 1 month frozen

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Sample must be free of clots and hemolysis.

Methodology
Clotting Time Measurement

Setup Schedule

Performed M, W & F (dayshift)

Report Available

Upon Completion of Analysis

Reference Range

32.2-48.7 seconds

Clinical Significance

Lupus anticoagulants (LA) are immunoglobulins that generally interfere with phospholipid-dependent in vitro coagulation tests, the most frequently used being the activated partial thromboplastin time (APTT) assay. The common association of LA with recurrent spontaneous abortions and idiopathic thromboembolic diseases underlies the importance of diagnostic tests capable of distinguishing these LA antibodies from anti-factor antibodies, factor deficiencies and heparin, since all four conditions may cause a prolongation of the APTT test.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.