A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Free Light Chains, Serum
Test CodeCPT Codes
83520 x 2
Includes
Preferred Specimen
Serum (Gold or Red Top Tube)
Minimum Volume
Transport Container
Serum (Gold or Red Top) Tube
Transport Temperature
Specimen Stability
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Methodology
Turbidimetric
Setup Schedule
Monday, Wednesday and Friday, 8:00 am - 3:00 pm upon receipt
Report Available
Reference Range
Kappa Free Light Chains: 3.30 - 19.40 mg/L
Lambda Free Light Chains: 5.71 - 26.30 mg/L
Kappa/Lambda Free Light Chain Ratio: 0.26 - 1.65
Clinical Significance
Elevated serum levels of monoclonal FLC are associated with malignant plasma cell proliferation (e.g. multiple myeloma), AL amyloidosis and light chain deposition disease. Raised serum levels of polyclonal FLC may be associated with autoimmune diseased sush as systemic lupus erythematosus. The appearance of higher levels of FLC in urine may be indicative of kidney disease or malignant lymphoproliferative disease such as multiple myeloma. The monoclonal urinary FLC associated with lymphoid malignancy is called Bence-Jones Protein.