Anti-Thrombin III

Test Code

ATIII

CPT Codes
85300

Preferred Specimen

1 Blue/ 1Lav

Minimum Volume

Blue top must be filled to Minimum Fill Indicator Line on tube.

Other Acceptable Specimens

none

Instructions

Outreach clients should double-spin the blue top plasma, remove the plasma from the RBC button, and freeze in a polypropylene tube.

Transport Container

Blue top; Polypropylene tube

Transport Temperature

Blue top - ambient; Polypropylene - frozen

Specimen Stability

Blue - 4 hours RT; Plasma - 8 hours RT, 1 month frozen

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Sample must be free of clots and hemolysis.

Methodology
Colorimetric

Setup Schedule

Performed 24/7

Report Available

Upon Completion of Analysis

Reference Range

71 - 122 %

Clinical Significance

Antithrombin III exerts a powerful and immediate inhibitory action on thrombin when heparin is present. Since the first report (1965) of a hereditary deficiency of AT III and its consequences, AT III has been considered an important parameter in spontaneous thromboembolic disorders. The hereditary deficiency, either quantitative or qualitative, is less common than the acquired deficiency. An acquired AT III deficiency has been described in DIC, septic shock, nephrotic syndrome, liver disease and in L-asparaginase treatments.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.