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Manganese, Serum
Test Code951
CPT Codes
83785
Preferred Specimen
2 mL serum collected in a no additive (royal blue-top) tube
Minimum Volume
0.7 mL
Other Acceptable Specimens
Plasma collected in: EDTA (royal blue-top) tube or sodium heparin (royal blue-top) tube
Instructions
Carefully clean skin prior to venipuncture. Avoid hemolysis. Avoid worksite collection.
Serum: Blood may be drawn into royal blue-top evacuated tube without additive, allow to clot and centrifuge within 4 hours of collection. Pour off plasma/serum into an acid-washed metal-free tube for transportation. Use powderless gloves.
Plasma: Follow the above instructions except that the sample does not go through the clotting process.
Serum: Blood may be drawn into royal blue-top evacuated tube without additive, allow to clot and centrifuge within 4 hours of collection. Pour off plasma/serum into an acid-washed metal-free tube for transportation. Use powderless gloves.
Plasma: Follow the above instructions except that the sample does not go through the clotting process.
Transport Container
Acid-washed, metal-free vial
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 7 days
Refrigerated: 30 days
Frozen: 60 days
Refrigerated: 30 days
Frozen: 60 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Sodium heparin lead-free (tan-top) tube
Methodology
Inductively Coupled Plasma/Mass Spectrometry (ICP/MS)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Wed, Fri; Report available: 2-6 days
Reference Range
<1.2 mcg/L
Clinical Significance
Manganese deficiency produces growth disorders, alters skeletal and cartilage formation, and impairs reproduction. Industrial workers absorb manganese mainly through the lungs.