Histamine, 24-Hour Urine [4946X]

Test Code

H24U

CPT Codes
83088

Includes

CPT code 81050 may be added at an additional charge for volume measurement

Preferred Specimen

4 mL aliquot of a preserved 24-hour urine collected in a plastic
leak-proof container

Patient Preparation
Avoid direct sunlight. Patient should refrain from taking allergy causing drugs, antihistamines, oral corticosteroids, and substances which block H2 receptors for at least 24 hours prior to specimen collection.

Minimum Volume

2 mL

Other Acceptable Specimens

Urine with no preservative

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 48 hours Refrigerated: 14 days Frozen: 14
days

Methodology

Immunoassay (IA)

FDA Status
This test was performed using a kit that has not been cleared or approved by the FDA. The analytical performance characteristics of this test have been determined by Quest Diagnostics. This test should not be used for diagnosis without confirmation by other medically established means.

Setup Schedule

Set up: Tues, Fri; Report available: 2-5 days

Reference Range

Histamine, 24-Hour Urine

0.006-0.131

mg/24 h

Creatinine, 24-Hour Urine

<3 Years	Not established
3-8 Years	0.10-0.80 g/24 h
9-12 Years	0.20-1.40 g/24 h
13-17 Years	0.40-1.90 g/24 h
>17 Years	0.50-2.15 g/24 h

Clinical Significance

Histamine is a mediator of the allergic response. Histamine release causes itching, flushing, hives, vomiting, syncope, and even shock. In addition, some patients with gastric carcinoids may exhibit high concentrations of histamine.

Performing Laboratory
Quest Diagnostics Nichols Inst San Juan Capistrano 33608 Ortega Highway San Juan Capistrano, CA 92675

Last Updated: February 20, 2023

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.