Amino Acid Analysis, LC/MS, CSF

Test Code

AAQSF

CPT Codes
82139 * This test code is for non-New York Patient testing. For New York patient testing, use test code 19768. *

Includes

Alanine, Alpha-Amino Adipic Acid, Alpha-Amino Butyric Acid, Arginine, Asparagine, Aspartic Acid, Beta-Alanine, Beta-Amino Isobutyric Acid, Citrulline, Gamma-Amino Butyric Acid, Glutamic Acid, Glutamine, Glycine, Histidine, Homocystine, Hydroxyproline, Isoleucine, Leucine, Lysine, Methionine, Ornithine, Phenylalanine, Proline, Sarcosine, Serine, Taurine, Threonine, Tryptophan, Tyrosine, Valine

Preferred Specimen

1 mL CSF

Minimum Volume

0.25 mL

Instructions

Patient age is required for correct reference range. Freeze CSF below -20°C.

Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable Refrigerated: 7 days Frozen: 30
days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis

Methodology

Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Mon-Fri a.m.; Report available: 6 days

Reference Range

See Laboratory Report

Clinical Significance

Amino acid analysis is necessary for the diagnosis of a variety of inborn errors of metabolism. These include, but are not limited to, Phenylketonuria, Tyrosinemia, Citrullinemia, Non-Ketotic Hyperglycinemia, Maple Syrup Urine Disease, and Homocystinuria. The assay is also key for the continued monitoring of treatment plans for these disorders and useful for assessing nutritional status of patients. Our methodology is highly accurate at very low levels as well as at elevated levels.

Performing Laboratory
Quest Diagnostics Nichols Inst San Juan Capistrano 33608 Ortega Highway San Juan Capistrano, CA 92675

Last Updated: February 20, 2023

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.