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von Willebrand Antigen, Multimeric
Test CodeVWFMA
Alias/See Also
LAB1111
CPT Codes
<p>85247</p>
Preferred Specimen
Specimen Type: Plasma Na Cit
Collection Container/Type: Light blue top (citrate)
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions:
- Completely fill tube. Underfilled tubes are unacceptable
- Centrifuge, remove plasma, and centrifuge plasma again.
- Aliquot plasma into a plastic vial leaving 0.25 mL in the bottom of centrifuged vial.
For complete instructions, see Platelet Poor Plasma Instructions.
Additional Information: Double-centrifuged specien is critical for accurate results as platelet contamination may cause spurious results.
Minimum Volume
0.2 mL
Instructions
Please submit a separate, frozen vial for each special coagulation assay ordered. Draw blood in a light blue-top tube containing 3.2% sodium citrate, mix gently by inverting 3-4 times. Centrifuge 15 minutes at 1500 g within one hour of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial(s). Freeze immediately and transport on dry ice.
Transport Container
Transport tube
Transport Temperature
Frozen
Specimen Stability
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 30 days
Methodology
Electrophoresis
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Mon-Fri; Report available: 4-8 days
Report Available
4-8 days
Reference Range
Normal
Clinical Significance
von Willebrand Disease is the most common hereditary bleeding disorder and it may also be acquired. Von Willebrand Factor (VWF) is critical for normal hemostasis; mediating platelet adhesion to the damaged endothelium and protecting Factor VIII from proteolytic degradation in circulation. VWF Multimeric Analysis is used to assist in categorizing disease subtype.
Performing Laboratory
Quest Diagnostics Nichols Institute 14225 Newbrook Drive Chantilly, VA 20153
Last Updated: February 17, 2023