A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #

Vitamin K

Test Code
VITK


Alias/See Also

LAB1110



CPT Codes
<p>84597</p>

Preferred Specimen

Patient Preparation: Fasting for a minimum of 8 hours required. Patient should refrain from eating liver and taking multivitamins or vitamin K at least 24 hours before sample collection.

Specimen Type: Plasma

Collection Container/Type: Lavender top (EDTA)

Submission Container/Tube:  Plastic vial

Specimen Volume: 1 mL

Collection Instructions: 

  1. Centrifuge within 1 hour of collection.
  2. Immediately separate plasma or serum from the cells into an amber transport tube to protect from light.
  3. Freeze. Do not thaw.
  4. Samples received frozen but not protected from light are acceptable.
  5. Transport plasma or serum to the laboratory frozen.

 

Specimen Type: Serum

Collection Container/Type: Gold SST

Submission Container/Tube:  Plastic vial

Specimen Volume: 1 mL

Collection Instructions: 

  1. Centrifuge within 1 hour of collection.
  2. Immediately separate plasma or serum from the cells into an amber transport tube to protect from light.
  3. Freeze. Do not thaw.
  4. Samples received frozen but not protected from light are acceptable.
  5. Transport plasma or serum to the laboratory frozen.


Patient Preparation
Fasting for a minimum of 8 hours required. Patient should refrain from eating liver and taking multivitamins or vitamin K at least 24 hours before sample collection.

Minimum Volume

0.5 mL



Other Acceptable Specimens
Plasma collected in a sodium heparin or lithium heparin (green-top) tube, protected from light • Serum, protected from light


Instructions

Centrifuge within 1 hour of collection. Immediately separate plasma or serum from the cells into an amber transport tube to protect from light. Freeze. Do not thaw. Samples received frozen but not protected from light are acceptable.

If unable to centrifuge immediately, sample should be covered with aluminum foil immediately and placed on ice until plasma or serum can be separated from cells.

Transport plasma or serum to the laboratory frozen.



Transport Container
Amber transport tube, light protected


Transport Temperature
Frozen


Specimen Stability

Room temperature: 24 hours


Refrigerated: 24 hours


Frozen: 90 days



Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Grossly lipemic • Gross hemolysis



Methodology

Chromatography/Mass Spectrometry

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.



FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up: Mon-Thurs, Sat; Report available: 3-4 days


Report Available

3-4 days



Reference Range
130-1500 pg/mL


Clinical Significance
Vitamin K is a required co-factor for the synthesis of factors 2, 7, 9, and 10 and proteins C and S. Deficiencies of vitamin K lead to bleeding. Coumadin® (warfarin) acts as an anticoagulant because it is a vitamin K antagonist.


Performing Laboratory
Quest Diagnostics Nichols Institute 14225 Newbrook Drive Chantilly, VA 20153


Last Updated: February 17, 2023


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.