| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Posaconazole
Test CodePOSAC
Alias/See Also
LAB11747
CPT Codes
<p>80187</p>
Preferred Specimen
Specimen Type: Serum Red
Collection Container/Type: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 2 mL
Minimum Volume
1 mL
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 72 hours
Refrigerated: 14 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum separator tubes (SST) • Other body fluids • Other specimen types
Methodology
Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Tues, Thurs, Sat.; Report available: 1-4 days
Report Available
2-5 days
Reference Range
after 7 days of treatment
| Target for prophylaxis purpose | trough level >0.7 mcg/mL |
| Target for salvage treatment | trough level >1.25 mcg/mL |
Clinical Significance
The antifungal drug posaconazole is indicated for prophylaxis of invasive aspergillus and candida infections in severely immunocompromised patients. It may also be used in the treatment of oropharyngeal candidiasis refractory to itraconazole and fluconazole. The chronic nature of fungal infections demands constant monitoring of posaconazole levels within a patient to ensure that adequate therapeutic levels of the drug are administered, absorbed and subsequently excreted.
Performing Laboratory
Quest Diagnostics Nichols Institute 14225 Newbrook Drive Chantilly, VA 20153
Last Updated: February 17, 2023