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Parietal Cell Antibody, ELISA
Test CodeGPCAB
Alias/See Also
LAB3138
CPT Codes
<p>83516</p>
Preferred Specimen
Specimen Type: Serum
Collection Container/Type
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions:
- Collect 1 mL serum from a red top (no additive) tube and place in a sterile, plastic, screw cap vial.
- Serum separator tube, plastic or glass is also accepted.
- Ship refrigerated (cold packs) only.
Minimum Volume
0.3 mL
Other Acceptable Specimens
1 mL Serum (Min0.3 mL)
SST Glass; Refrigerated;
-OR-
1 mL Serum (Min0.3 mL)
SST Plastic; Refrigerated;
SST Glass; Refrigerated;
-OR-
1 mL Serum (Min0.3 mL)
SST Plastic; Refrigerated;
Instructions
Collect 1 mL serum from a red top (no additive) tube and place in a sterile, plastic, screw cap vial. Serum separator tube, plastic or glass is also accepted. Ship refrigerated (cold packs) only.
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 8 hours
Refrigerated: 14 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Lipemia
Methodology
Immunoassay (IA)
Setup Schedule
Tuesday, Thursday, Saturday Afternoon
Report available: Next Day
Report available: Next Day
Report Available
1-4 days
Reference Range
| ≤20.0 U | Negative | |
| 20.1-24.9 U | Equivocal | |
| ≥25.0 U | Positive | |
Clinical Significance
Gastric Parietal Cell Antibodies are found in 90% of patients with pernicious anemia. They are also found in autoimmune chronic atrophic gastritis preceding pernicious anemia. The antigenic target is the H+/K+ ATPase gastric proton pump responsible for parietal cell acid generation in the stomach.
Performing Laboratory
Quest Diagnostics Nichols Institute 14225 Newbrook Drive Chantilly, VA 20153
Last Updated: February 17, 2023