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C-Peptide
Test CodeCPEPE
Alias/See Also
LAB521
CPT Codes
<p>84681</p>
Preferred Specimen
Patient Preparation: Patients should fast 12 hours prior to collection.
Specimen Type: Serum
Collection Container/Type
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Patient Preparation
Patients should fast 12 hours prior to collection.
Minimum Volume
0.5 mL
Transport Container
Plastic screw-cap vial
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 4 days
Refrigerated: 7 days
Frozen: 7 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
0.80-3.85 ng/mL
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Mon-Sat a.m.; Report available: Next day
Report Available
Next day
Reference Range
0.80-3.85 ng/mL
Clinical Significance
C-Peptide is useful in the evaluation of pancreatic beta cell function (e.g., helping distinguish type 1 from type 2 diabetes mellitus, or monitoring patients who have received islet cell or pancreatic transplants) and for determining the source of insulin in patients with hyperinsulinemic hypoglycemia (e.g., distinguishing insulin-secreting tumors from exogenous insulin administration). It is also sometimes measured as an additional means (more resistant to hemolysis than is insulin itself) for evaluating glucose tolerance tests.
Performing Laboratory
Quest Diagnostics Nichols Institute 14225 Newbrook Drive Chantilly, VA 20153
Last Updated: February 17, 2023