Coccidioides Antibody, Complement Fixation, Serum

Test Code

CCIDA

CPT Codes
<p>86635</p>

Preferred Specimen

Specimen Type: Serum

Collection Container/Type

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Additional Information:

For CSF, use test code 5295X Coccidioides Antibody, Complement Fixation, CSF.

Minimum Volume

0.2 mL

Instructions

For CSF, use test code 5295X Coccidioides Antibody, Complement Fixation, CSF.

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days

Refrigerated: 14 days

Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Grossly lipemic • Grossly icteric

Methodology

Complement Fixation (CF)

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Tues-Sat; Report available: 2-5 days

Report Available

2-5 days

Limitations

False-negatives may occur in patients with solitary pulmonary lesions. Patients with active histoplasmosis may generate cross reactions. Elevated serum antibodies may be present in patients with meningeal coccidiocomycosis.

Reference Range

<1:2 titer

Interpretive Criteria

<1:2	Antibody Not Detected
≥1:2	Antibody Detected

Clinical Significance

Infection by Coccidioides immitis can produce a spectrum of disease, with most patients being asymptomatic and some developing disseminated disease, including pneumonia and meningitis.

Performing Laboratory
Quest Diagnostics Nichols Institute 14225 Newbrook Drive Chantilly, VA 20153

Last Updated: February 17, 2023

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.