| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Cardiolipin Antibodies (IgA, IgG, IgM)
Test CodeCARPN
Alias/See Also
LAB464
CPT Codes
<p>86147 (x3)</p>
Preferred Specimen
Specimen Type: Platelet-poor plasma
Collection Container/Type: Light-blue top (3.2% sodium citrate)
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Specimen Type: Serum
Collection Container/Type
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Minimum Volume
0.5 mL
Other Acceptable Specimens
Serum
Transport Container
Plastic screw-cap vial
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 5 days
Refrigerated: 14 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Tues-Sat; Report available: 3-5 days
Report Available
Next day
Reference Range
Cardiolipin Antibody (IgA)
Cardiolipin Antibody (IgG)
Cardiolipin Antibody (IgM)
| Value | Interpretation |
| <20.0 APL-U/mL | Antibody not detected |
| ≥20.0 APL-U/mL | Antibody detected |
Cardiolipin Antibody (IgG)
| Value | Interpretation |
| <20.0 GPL-U/mL | Antibody not detected |
| ≥20.0 GPL-U/mL | Antibody detected |
Cardiolipin Antibody (IgM)
| Value | Interpretation |
| <20.0 MPL-U/mL | Antibody not detected |
| ≥20.0 MPL-U/mL | Antibody detected |
Clinical Significance
Cardiolipin antibodies (CA) are seen in a subgroup of patients with autoimmune disorders, particularly systemic lupus erythematosus (SLE), who are at risk for vascular thrombosis, thrombocytopenia, cerebral infarct and/or recurrent spontaneous abortion. Elevations of CA associated with increased risk have also been seen in idiopathic thrombocytopenic purpura, rheumatoid and psoriatic arthritis, and primary Sjögren's syndrome.
Performing Laboratory
Quest Diagnostics Nichols Institute 14225 Newbrook Drive Chantilly, VA 20153
Last Updated: February 17, 2023