A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #

Rectal Swab Carbapenemase Surveillance PCR

Test Code
CRPCR


Alias/See Also
Epic: LAB14554


Includes
Real-time polymerase chain reaction (PCR) for the qualitative detection and differentiation of the blaKPC, blaNDM, blaVIM, blaOXA-48, and blaIMP gene sequences associated with carbapenem-non-susceptibility in gram negative bacteria. 


Preferred Specimen

Specimen Type: Swab
Source: Rectal, perirectal
Collection Container: Culture transport swab (dual swab, LQ Stuart, plastic applicators, rayon tipped; Cepheid catalog number 900-0370).
Specimen Volume: Swab




Instructions
Collection Instructions: 
  1. Rectal collection: Carefully insert both swab tips approximately 1 cm beyond the anal sphincter and rotate gently
     - OR -
    Perirectal collection: Carefully inser both swab tips no more than 1 cm into the anal opening before the anal sphincter and rotate gently.
  2. Heavily soiled swabs are unaccpetable.  See acceptable swabs below.
  3. Label swab with patient information.
  4. Transport o the laboratory at room temperature.
Additional Information:
  • The following are examples of acceptable specimens:


Specimen Stability

Room temperature: 5 days
Refrigerated: Unacceptable
Frozen: Unaccptable




Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Highly soiled swab specimens:




Setup Schedule

Daily




Report Available

1 day




Reference Range
Not detected


Clinical Significance
This test utilizes real-time PCR for the detection and differentiation of gene sequences associated with carbapenem-non-susceptibility in Enterobacteriaceae, Pseudomonas aeruginosa and Acinetobacter baumannii. Targets include blaKPC, blaNDM, blaVIM, blaOXA-48 (and blaOXA-181), and blaIMP (excluding IMP-7, IMP-13, IMP-14). Detection of these gene sequences does not indicate the presence of viable organisms. This assay does not report variants of these gene sequences. Mutations or polymorphisms may affect detection of current, new, or unknown variants, resulting in a false negative result. This test is for Infection control surveillance purposes only and should not be used to make treatment decisions. The performance of the Xpert Carba-R Assay has not been evaluated with rectal swab specimens from pediatric patients.


Performing Laboratory

Inova Laboratories

2832 Juniper Street

Fairfax, VA 22031




Last Updated: July 19, 2023
Last Review: N. Wolford, April 10, 2023


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.