Gentamicin, Random

Test Code
GENTR


Alias/See Also
Epic: LAB27


Preferred Specimen

Specimen Type: Serum
Collection Container: Serum gel 
Specimen Volume: 3 mL




Minimum Volume

0.2 mL




Other Acceptable Specimens

Collection Container: Red top




Instructions
Collection Instructions
  1. Centrifuge and separate cells after clot formation and within 4 hours of collection. 

Additional Information
  1. Provide date and time of last dose.


Transport Container
Plastic vial


Specimen Stability

Room temperature: Undefined
Refrigerated: 7 days
Frozen: 14 days




Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Unlabeled, mislabeled, wrong tube type, QNS, severely (grossly) hemolyzed samples, and any sample from which the lipid layer has not been removed.




Methodology

Chemiluminescent Microparticle Immunoassay (CMIA) 



Setup Schedule

Daily




Report Available

Same day




Reference Range
Gentamicin, Peak
Therapeutic: 4.0 - 12.0 μg/mL

Gentamicin, Trough
Therapeutic: 1.2 - 2.0 μg/mL


Clinical Significance
Gentamicin is an aminoglycoside antibiotic which exhibits high potency and a broad spectrum bacterial action against both gram-negative and gram-positive organisms.  It exhibits a narrow therapeutic index which makes its use hazardous, especially in patients with impaired renal function.  In addition, the dose-serum level profile curve of gentamicin is unpredictable, both in terms of peak-serum levels and elimination half-life from plasma.  Gentamicin is used in the treatment of serious infections involving aminoglycoside-sensitive organisms.  Monitoring gentamicin concentration in serum or plasma, along with careful clinical assessment, is the most effective means of ensuring adequate therapy.


Performing Laboratory

Inova Laboratories

2832 Juniper Street

Fairfax, VA 22031




Last Updated: July 12, 2023
Last Review: N. Wolford, July 12, 2023


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.