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Wright Stain For WBC
Test CodeWSWBC
Alias/See Also
Epic:LAB2460
Eosinophils, Random, Urine
Eosinophils
Eosinophils, Random, Urine
Eosinophils
Preferred Specimen
Specimen Type: Urine
Collection Container: Red/Yellow tube (UA-preservative)
Specimen Volume: 8 mL
Minimum Volume
1 mL
Other Acceptable Specimens
Specimen Type: Urine
Collection Container: Sterile container
Instructions
- Preferred specimen is a mid-stream, clean catch sample.
- The first morning specimen is most concentrated and is preferred, although fresh random samples are acceptable. If testing is delayed (>2hours after collection), the specimen without preservatives should be refrigerated for up to 4 hours.
- If a urine culture is needed, submit a separate order and specimen in gray-top urine culture tube. UA-preservative tubes are not acceptable for culture testing.
Specimen Stability
Preserved & Unpreserved Urine
Room temperature: 2 hours
Refrigerated: 4 hours
Frozen: Unacceptable
Setup Schedule
Daily
Report Available
Same day
Limitations
Eosinophils in urine are sometimes difficult to recognize since the orange granules look paler in urine than in peripheral blood smears. A combination of granule color and size, nucleus shape and cell size may be needed to identify urine eosinophils.
Reference Range
None seen
Clinical Significance
The examination of urine sediments has been studied in an effort to diagnose renal allograft rejections. This concept is based on the fact that the skin graft rejection has sometimes been associated with peripheral eosinophila as well as prominent eosinophilic infiltration below the graft site.
Eosinophils may be seen in the urine sediments of patients with drug-induced interstitial nephritis, including hypersensitivity to drugs such as penicillin and its derivatives, and with other acute genitourinary tract disorders. Detection is important, since treatment is effectively achieved by discontinuing the drug.
Eosinophils may be seen in the urine sediments of patients with drug-induced interstitial nephritis, including hypersensitivity to drugs such as penicillin and its derivatives, and with other acute genitourinary tract disorders. Detection is important, since treatment is effectively achieved by discontinuing the drug.
Performing Laboratory
Inova Laboratories
2832 Juniper Street
Fairfax, VA 22031
Last Updated: May 10, 2023
Last Review: N. Wolford, May 10, 2023