A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #

Sirolimus

Test Code
RAPAM


Alias/See Also
Epic: LAB875

Rapamune
Rapamycin


Preferred Specimen

Specimen Type: Whole blood EDTA
Collection Container: Lavender top (EDTA)
Specimen Volume: 3 mL




Minimum Volume

0.35 mL




Instructions
  1. Samples should be drawn immediately before next dose.
  2. Do not centrifuge.
  3. Send sample in original collection container.


Specimen Stability

Room temperature: Unacceptable
Refrigerated: 7 days
Frozen: Not defined




Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Unlabeled, mislabeled, wrong tube type, clotted, QNS, exceeds specimen/stability requirements.




Methodology

Sirolimus is an immunosuppressive drug for renal transplant immunosuppressive therapy. Because of potential toxic effects associated with high trough levels of sirolimus, therapeutic drug monitoring of sirolimus immunosuppressive therapy has been recommended. Sirolimus is a macrocyclic lactone fermentation product of Streptomyces hygroscopicus, first discovered in the soil of Rapa Nui.



Setup Schedule

Daily




Report Available

Same day




Reference Range

5.0 - 15.0 ng/mL




Performing Laboratory

Inova Laboratories

2832 Juniper Street

Fairfax, VA 22031




Last Updated: April 19, 2023
Last Review: N. Wolford, April 19, 2023


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.