A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #

Platelet Aggregation

Message

Important Note

  • Testing must be scheduled.  Please call Inova Laboratories at 703-645-6175, option 2 to schedule an appointment.


Test Code
PLAGO


Alias/See Also
Epic: LAB2386


Preferred Specimen

Requires both plasma and whole blood.

Specimen Type: Platelet-poor plasma
Collection Container: Light blue top (citrate)
Specimen Volume: 6 x 4.5

Specimen Type: Whole blood EDTA
Collection Container: Lavender top (EDTA)
Specimen Volume: 3 mL




Patient Preparation
Patient should be resting, fasting and non-smoking.  Avoid taking an prescription or over the counter medications known to affect platelet function for 10 days to 2 weeks prior to the test (unles otherwise instructed by your provider; i.e. the aim of testing is to demonstrate drug-induced inhibition).  


Instructions
  1. Submit specimens to the testing department as whole blood in their original collection containers.  Do no spin, do not aliquot.
  2. ​Specimens should be drawn with a minimum of trauma or stasis at the venipuncture site and anticoagulated with 3.2% sodium citrate, in the ratio of 1 part anticoagulant to 9 parts of blood.
  3. Plastic or non-contact surfaced (siliconized) material should be used throughout in order to minimize activation of the platelets during sample preparation.


Specimen Stability

Testing must be completed within 3 hours of collection.




Setup Schedule

Tuesday




Report Available

1 day




Limitations
Interfering Substances
  • Non-steroidal anti-inflammatory drugs
    ​Aspirin and all OTC preparations containing acetylsalicylic acid ; reversible cyclooxygenase inhibitors such as indomethacin, ibuprofen, sulindac and naproxen
  • Antibiotics
    Penicillin's, cephalosporin's, nitrofurantoin, Miconazole
  • Thienopyridines
    Ticlopidine, clopidogrel
  • GPIIb/IIIa antagonists
    Abciximab, tirofiban, eptifibatide
  • Drugs that affect platelet cAMP levels
    Prostacyclin, iloprost, dipyridamole, cilostazol
  • Anticoagulants and fibrinolytic agents
    Heparin, streptokinase, tissue plasminogen activator, urokinase, e-aminocaproic acid
  • Cardiovascular drugs
    Nitroglycerin, isosorbide dinitrate, propranolol, nitroprusside, nifedipine, verapamil, diltiazem, quinidine
  • Volume expanders
    Dextran, hydroxyethyl starch
  • Psychotropic drugs and anesthetics
    Psychotropic drugs: imiprimine, amitriptyline, nortryptaline, chlorpromazine, flufenazine, trifluoperazine, and haloperidol
    Anesthetics: dibucaine, tetracaine, metycaine, cyclaine, butacaine, nepercaine, procaine, cocaine, plaquenil, and halothane
  • Chemotherapeutic agents
    Mithramycin, daunorubicin, BCNU
  • Miscellaneous drugs
    Serotonin antagonists
    Antihistamines
    Radiographix contrast agent
  • Foods/Herbals
    Alcohol
    Caffeine (Methylxanthine)
    Garlic, Onion, Ginger
    Fish Oil
    Vitamin E


Reference Range
See laboratory report


Performing Laboratory

Inova Laboratories

2832 Juniper Street

Fairfax, VA 22031




Last Updated: May 9, 2023
Last Review: N. Wolford, May 9, 2023


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.