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Hepatitis A IgG Antibody
Test CodeHAVG
Alias/See Also
Epic: LAB12911
Preferred Specimen
Specimen Type: Serum
Collection Container: Serum gel
Specimen Volume: 3 mL
Minimum Volume
0.5 mL
Instructions
Centrifuge and separate cells after clot formation and within 4 hours of collection
Transport Container
Plastic vial
Specimen Stability
Room temperature: 4 days
Refrigerated: 8 days
Frozen: >8 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Unlabeled, mislabeled, wrong tube type, hemolyzed, QNS, exceeds specimen/stability requirements.
Methodology
Chemiluminescent microparticle immunoassay
Setup Schedule
Daily
Report Available
Same day
Reference Range
Non-reactive
Clinical Significance
Transmission of the Hepatitis A virus is via the fecal-oral route, and infection occurs mainly due to contaminated food or poor sanitary conditions. The virus replicates in the liver and is shed in the stool. Incubation period ranges from 15-40 days. Symptoms last approximately 2 weeks and include hepatomegaly, jaundice, dark urine, fatigue, and gastrointestinal disturbances. At the onset of symptoms, antibody to HAV is detectable, largely compromised of IgM subclass. HAV IgM is detectable for 3-6 months, but HAV IgG can persist indefinitely. The anti-HAVG assay is most useful as an aid in the diagnosis of previous hepatitis A infection or in the identification of HAV-susceptible individuals for vaccination.
Performing Laboratory
Inova Laboratories
2832 Juniper Street
Fairfax, VA 22031
Last Updated: March 7, 2023
Last Review: N. Wolford, March 7, 2023