Vitamin B 1 (Thiamine), Blood, LC/MS/MS

Test Code

THIAM

Alias/See Also

LAB745

CPT Codes
<p>84425</p>

Preferred Specimen

Patient Preparation: Overnight fasting is required.

Specimen Type: Whole Blood EDTA

Collection Container/Type: Lavender top (EDTA)

Submission Container/Tube: Amber plastic vial

Specimen Volume: 2 mL

Collection Instructions:

Transfer whole blood to amber transport tube. If amber tube is not available, wrap tube in aluminum foil to protect from light.
Freeze immediately.

Additional Information:

Proted from light & freeze immediately

Patient Preparation
Overnight fasting is required

Minimum Volume

1 mL

Instructions

Transfer whole blood to amber transport tube. If amber tube is not available, wrap tube in aluminum foil to protect from light. Freeze immediately.

Transport Container

Amber transport tube or foil wrapped tube - light-protected

Transport Temperature

Frozen

Specimen Stability

Room temperature: 72 hours

Refrigerated: 5 days

Frozen: 35 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Received room temperature and not protected from light • Received refrigerated and not protected from light

Methodology

Chromatography/Mass Spectrometry

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Mon-Sat; Report available: 2-3 days

Report Available

2-3 days

Reference Range

78-185 nmol/L

Clinical Significance

Vitamin B1 is required for branched-chain amino acid and carbohydrate metabolism. Vitamin B1 deficiency is most often due to alcoholism or chronic illness. In the early stage, patients with vitamin B1 deficiency exhibit anorexia, irritability, apathy, and generalized weakness. Prolonged deficiency causes beriberi.

Performing Laboratory
Quest Diagnostics Nichols Institute 14225 Newbrook Drive Chantilly, VA 20153

Last Updated: October 15, 2019

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.