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Cardiolipin Antibody (IgG)
Test CodeCPT Codes
<p>86147</p>
Preferred Specimen
Specimen Type: Plasma, Sodium Citrate
Collection Container/Type
Preferred: Light-blue top (3.2% sodium citrate)
Acceptable: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Minimum Volume
0.5 mL
Other Acceptable Specimens
Transport Temperature
Specimen Stability
Room temperature: 4 days
Refrigerated: 7 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic
Methodology
Immunoassay (IA)
Setup Schedule
Tuesday - Saturday
Report Available
Next day
Reference Range
Cardiolipin Antibody IgG
| ≤14 GPL | Negative |
| 15-20 GPL | Indeterminate |
| 21-80 GPL | Low to medium positive |
| >80 GPL | High positive |
Clinical Significance
Cardiolipin antibodies (CA) are seen in a subgroup of patients with autoimmune disorders, particularly Systemic Lupus Erythematosus (SLE), who are at risk for vascular thrombosis, thrombocytopenia, cerebral infarct and/or recurrent spontaneous abortion. Elevations of CA associated with increased risk have also been seen in idiopathic thrombocytopenic purpura, rheumatoid and psoriatic arthritis, and primary Sjögren's syndrome.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153
Last Updated: February 22, 2012