Cardiolipin Antibody (IgA)

Test Code
CDLPA


Alias/See Also

LAB1734



CPT Codes
<p>86147</p>

Preferred Specimen

Specimen Type: Plasma

Collection Container/Type: Light-blue top (3.2% sodium citrate)

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

 

 

Specimen Type: Serum

Collection Container/Type

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL



Minimum Volume

0.5 mL



Other Acceptable Specimens
Serum


Transport Temperature
Room temperature


Specimen Stability

Room temperature: 5 days

Refrigerated: 14 days

Frozen: 30 days



Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Grossly lipemic



Methodology

Immunoassay (IA)



Setup Schedule
Set up: Tues-Sat; Report available: 3-5 days


Report Available

Next day



Reference Range
Value Interpretation
<20.0 APL-U/mL Antibody not detected
≥20.0 APL-U/mL Antibody detected


Clinical Significance

Cardiolipin antibodies (CA) are seen in a subgroup of patients with autoimmune disorders, particularly Systemic Lupus Erythematosus (SLE), who are at risk for vascular thrombosis, thrombocytopenia, cerebral infarct and/or recurrent spontaneous abortion. Elevations of CA associated with increased risk have also been seen in idiopathic thrombocytopenic purpura, rheumatoid and psoriatic arthritis, and primary Sjögren's syndrome.



Performing Laboratory
Quest Diagnostics Nichols Institute 14225 Newbrook Drive Chantilly, VA 20153


Last Updated: February 22, 2012


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.