Erythropoietin (EPO)

Test Code
EPOSS


Alias/See Also

LAB873



CPT Codes
<p>82668</p>

Preferred Specimen

Specimen Type: Serum

Collection Container/Type

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Additional Information: Due to diurnal variation, it is recommended that specimens be collected between 7:30 a.m. and noon.



Minimum Volume

0.5 mL



Instructions
Due to diurnal variation, it is recommended that specimens be collected between 7:30 a.m. and noon.


Transport Container
Plastic screw-cap vial


Transport Temperature
Room temperature


Specimen Stability

Room temperature: 10 days

Refrigerated: 18 days

Frozen: 28 days



Methodology

Immunoassay (IA)



Setup Schedule
Set up: Mon, Wed, Fri, Sat; Report available: 2-4 days


Report Available

2-4 days



Reference Range
  Male (mIU/mL) Female (mIU/mL)
<1 Year Not established Not established
1-3 Years 1.7-17.9 2.1-15.9
4-6 Years 3.5-21.9 2.9-8.5
7-9 Years 1.0-13.5 2.1-8.2
10-12 Years 1.0-14.0 1.1-9.1
13-15 Years 2.2-14.4 3.8-20.5
16-18 Years 1.5-15.2 2.0-14.2
>18 Years 2.6-18.5 2.6-18.5


Clinical Significance
Elevated levels of serum erythropoietin (EPO) occur in patients with anemias due to increased red cell destruction in hemolytic anemia and also in secondary polycythemias associated with impaired oxygen delivery to the tissues, impaired pulmonary oxygen exchange, abnormal hemoglobins with increased oxygen affinity, constriction of the renal vasculature, and inappropriate EPO secretion caused by certain renal and extrarenal tumors. Normal or depressed levels may occur in anemias due to increased oxygen delivery to tissues, in hypophosphatemia, and in polycythemia vera.


Performing Laboratory
Quest Diagnostics Nichols Institute 14225 Newbrook Drive Chantilly, VA 20153


Last Updated: February 22, 2012


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.