Centromere B Antibody

Test Code

CHRU

CPT Codes
86235

Preferred Specimen

1 mL serum

Minimum Volume

0.5 mL

Transport Container

Plastic screw-cap vial

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 4 days Refrigerated: 14 days Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Grossly lipemic • Grossly icteric

Methodology

Immunoassay (IA)

Setup Schedule

Set up: Mon-Sat a.m.; Report available: Next day

Limitations

As many as 15% of health controls may have low or slightly elevated antibody levels.

Reference Range

<1.0 AI Negative

Clinical Significance

Centromere B Antibody is diagnostic for the form of scleroderma known as CREST (calcinosis, Raynaud's phenomenon, esophageal immotility, sclerodactyly, and telangiectasia).

Performing Laboratory
Quest Diagnostics Nichols Institute 14225 Newbrook Drive Chantilly, VA 20153

Last Updated: February 22, 2012

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.