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Kappa/Lambda Light Chains, Free with Ratio Reflex to Immunofixation, Serum
Test CodeKLLCF
CPT Codes
<p>83521 (x2)</p>
Includes
If Kappa/Lambda, Free is <0.26 or >1.65, then Immunofixation, Serum will be performed at an additional charge (CPT code(s): 86334).
Preferred Specimen
Specimen Type: Serum
Collection Container/Type
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 2 mL
Minimum Volume
1 mL
Transport Container
Plastic screw-cap vial
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 72 hours
Refrigerated: 7 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • Microbially contaminated serum • Specimens containing heavy visible particulate
Methodology
Immunoturbidimetric
Setup Schedule
Set up: Mon-Fri; Report available: 2-7 days
Report Available
2-7 days
Reference Range
Kappa Light Chain, Free, Serum | 3.3-19.4 mg/L |
Lambda Light Chain, Free, Serum | 5.7-26.3 mg/L |
Kappa/Lambda Light Chains Free with Ratio, Serum | 0.26-1.65 |
Clinical Significance
Measurement of the amounts of the different light chain types aids in the diagnosis and monitoring of multiple myeloma, lymphocytic neoplasms, Waldenstrom's macroglobulinemia, and connective tissue diseases, such as systemic lupus erythematosus.
Performing Laboratory
Quest Diagnostics Nichols Institute 14225 Newbrook Drive Chantilly, VA 20153
Last Updated: February 23, 2012