A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Mycophenolic Acid, LC/MS/MS
Test CodeAlias/See Also
LAB3282
CPT Codes
<p>80180</p>
Includes
Preferred Specimen
Patient Preparation: Optimum time to collect sample: 1/2 hour to 1 hour before next dose (trough) at steady-state (3-5 days after treatment with oral doses)
Specimen Type: Serum Red
Collection Container/Type: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions:
- Collect blood in a plain red-top tube (no gel).
- Allow blood to clot at 15-28° C for 20-30 minutes.
- Centrifuge at 25-28° C (2200-2500 rpm, 1000 x g) for 8-10 minutes.
- Transfer serum to polypropylene or polyethylene transport tube.
- Ship refrigerated (cold packs).
Additional Information:
- Samples left at room temperature for >72 hours are unacceptable.
Specimen Type: Plasma
Collection Container/Type
Preferred: Green top (Sodium heparin)
Acceptable: Lavender top (EDTA)
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions:
- Draw blood into an EDTA (lavender-top) tube.
- Separate cells by centrifuge at 18-25° C (2500-2800 rpm) for 5-10 minutes.
- Transfer plasma to polypropylene or polyethylene transport tube.
- Ship refrigerated (cold packs).
Additional Information:
- Samples left at room temperature for >72 hours are unacceptable.
Patient Preparation
Optimum time to collect sample: 1/2 hour to 1 hour before next dose (trough) at steady-state (3-5 days after treatment with oral doses)
Minimum Volume
0.5 mL
Other Acceptable Specimens
Instructions
Plasma (acceptable): Draw blood into an EDTA (lavender-top) tube. Separate cells by centrifuge at 18-25° C (2500-2800 rpm) for 5-10 minutes. Transfer plasma to polypropylene or polyethylene transport tube. Ship refrigerated (cold packs). Samples left at room temperature for >72 hours are unacceptable.
Transport Container
Transport Temperature
Specimen Stability
Room temperature: 72 hours
Refrigerated: 14 days
Frozen: 60 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Lipemia • Improperly labeled specimens • Specimens left at room temperature >72 hours • Gel barrier/serum separator tube (SST)
Methodology
Chromatography/Mass Spectrometry
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Report Available
2 days
Reference Range
Mycophenolic Acid | 1.0-3.5 mcg/mL |
MPA Glucuronide | 35.0-100.0 mcg/mL |
Clinical Significance
Performing Laboratory
Quest Diagnostics Nichols Institute 14225 Newbrook Drive Chantilly, VA 20153
Last Updated: February 23, 2012