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Menorrhagia Screen with Consultation
Test Code19651
CPT Codes
85240, 85245, 85246, 85270, 85610, 85730. Dependent on the complexity of the consultation, 81503 or 81504 or 81505 may be assigned. 81506 may also be billed if high complexity with more than 60 minutes of time spent for the consultation.
Includes
Activated Partial Thromboplastin Time; Prothrombin Time with INR: Factor XI Activity; von Willebrand Factor Antigen; Ristocetin Cofactor Activity; Factor VIII Activity
An interpretive coagulation report by a Quest Diagnostics coagulation expert is part of this panel. Clinical history may be submitted when ordered.
An interpretive coagulation report by a Quest Diagnostics coagulation expert is part of this panel. Clinical history may be submitted when ordered.
Preferred Specimen
1 mL platelet-poor plasma collected in each of three separate 3.2% sodium citrate (light blue-top) tubes
Minimum Volume
0.5 mL (x3)
Instructions
Collect blood in 3 sodium citrate tubes (blue-top); tubes must be filled to capacity to insure correct blood to anticoagulant ratio. Centrifuge whole blood at 1500g for 15 minutes. Avoiding the buffy coat, transfer plasma, using a plastic pipette, into a new plastic tube and repeat centrifugation. Aliquot plasma using a plastic pipette into 3 new plastic vials and freeze.
For preparation of platelet poor plasma and calculations for the collection of sodium citrate tubes from individuals with elevated Hct, refer to website Quest Diagnostics Nichols Institute Directory of Services under Specimen Collection section, Coagulation Testing, for further information on specimen processing.
Specimens must remain frozen during storage and shipment. All requests for coagulation assays should include a brief patient history and other pertinent clinical information.
For preparation of platelet poor plasma and calculations for the collection of sodium citrate tubes from individuals with elevated Hct, refer to website Quest Diagnostics Nichols Institute Directory of Services under Specimen Collection section, Coagulation Testing, for further information on specimen processing.
Specimens must remain frozen during storage and shipment. All requests for coagulation assays should include a brief patient history and other pertinent clinical information.
Transport Temperature
Frozen
Specimen Stability
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 14 days
Refrigerated: Unacceptable
Frozen: 14 days
Methodology
Clotting Assay • Immunoturbidimetric • Platelet Agglutination • Photo/Optical • Photometric Clot Detection
Setup Schedule
Set up and Report available: See individual assays
Reference Range
See Laboratory Report
Clinical Significance
This profile examines the most common causes of coagulation-associated menorrhagia: von Willebrand's disease, factor VIII deficiency (Hemophilia A carrier), and factor XI deficiency. When all of these tests are normal and the patient presents with spontaneous ecchymoses and mucous membrane bleeding, a platelet dysfunction (inherited or acquired) should be considered.
