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Androstenedione, Response to ACTH Stimulation
Test Code19511
CPT Codes
82157 (x2)
Includes
Androstenedione, Baseline
Androstenedione, 60 Minutes
Androstenedione, 60 Minutes
Preferred Specimen
1 mL serum per specimen collected in a red-top tube (no gel)
Minimum Volume
0.25 mL each specimen
Other Acceptable Specimens
Plasma collected in: EDTA (lavender-top), EDTA (royal blue-top), sodium heparin (green-top), or lithium heparin (green-top) tube
Instructions
Draw blood in a no additive (red-top) tube. Separate serum after clotting. Ship serum refrigerated or frozen. Do not submit glass tubes. An early morning specimen is preferred.
Draw baseline specimen. Draw another specimen 60 minutes after stimulation.
Note: Cortrosyn (Cosyntropin) not supplied by the laboratory.
This test cannot be collected at a Patient Service Center.
Draw baseline specimen. Draw another specimen 60 minutes after stimulation.
Note: Cortrosyn (Cosyntropin) not supplied by the laboratory.
This test cannot be collected at a Patient Service Center.
Transport Container
Transport tube(s)
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 72 hours
Refrigerated: 28 days
Frozen: 2 years
Refrigerated: 28 days
Frozen: 2 years
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Samples collected in serum separator tubes (SST)
Methodology
Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Mon-Sat; Report available: 4-7 days
Reference Range
See Laboratory Report
Clinical Significance
Androstenedione may be useful in evaluating patients with androgen excess and managing patients with congenital adrenal hyperplasia (CAH),
