Fibrinogen Antigen, Nephelometry

Test Code

37801

CPT Codes
85385

Preferred Specimen

1 mL plasma collected in a 3.2% sodium citrate (light blue-top) tube

Patient Preparation
Overnight fasting is required.

Minimum Volume

0.5 mL

Instructions

Avoid hemolysis and lipemia.

Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable
Refrigerated: 72 hours
Frozen: 90 days

Methodology
Nephelometry

Setup Schedule

Set up: Mon-Sat; Report available: Next day

Reference Range

Fibrinogen Antigen, Neph	<350 mg/dL
Risk
Optimal	< 350 mg/dL
High	≥ 350 mg/dL

Adult cardiovascular event risk category cut points (optimal, high) are based on Siemens BN II and BN ProSpec® system package insert.

Clinical Significance

Low levels of fibrinogen are associated with bleeding most commonly secondary to liver disease or Disseminated Intravascular Coagulation (DIC). Fibrinogen is an acute phase reactant and thus elevated levels may be associated with inflammation. Increased concentrations are also associated with increased risk of atherosclerosis.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.